Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation

Human induced pluripotent stem cells (hiPSCs) are used to study organogenesis and model disease as well as being developed for regenerative medicine. Endothelial cells are among the many cell types differentiated from hiPSCs, but their maturation and stabilization fall short of that in adult endothe...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Tiemeier, Gesa L., Wang, Gangqi, Dumas, Sébastien J., Sol, Wendy M.P.J., Avramut, M. Cristina, Karakach, Tobias, Orlova, Valeria V., van den Berg, Cathelijne W., Mummery, Christine L., Carmeliet, Peter, van den Berg, Bernard M., Rabelink, Ton J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895683/
https://ncbi.nlm.nih.gov/pubmed/31680061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.10.005
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