Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation

Human induced pluripotent stem cells (hiPSCs) are used to study organogenesis and model disease as well as being developed for regenerative medicine. Endothelial cells are among the many cell types differentiated from hiPSCs, but their maturation and stabilization fall short of that in adult endothe...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Tiemeier, Gesa L., Wang, Gangqi, Dumas, Sébastien J., Sol, Wendy M.P.J., Avramut, M. Cristina, Karakach, Tobias, Orlova, Valeria V., van den Berg, Cathelijne W., Mummery, Christine L., Carmeliet, Peter, van den Berg, Bernard M., Rabelink, Ton J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895683/
https://ncbi.nlm.nih.gov/pubmed/31680061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.10.005
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