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NEK2 promotes proliferation, migration and tumor growth of gastric cancer cells via regulating KDM5B/H3K4me3

The mechanisms of how Never in Mitosis (NIMA) Related Kinase 2 (NEK2) coordinates altered signaling to malignant gastric cancer (GC) transformation remain unclear. Overexpression of NEK2 and KDM5B were observed in GC cell lines with high sensitivity to NEK2 inhibitors. Here we investigated the biolo...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Li, Yiwei, Chen, Lijuan, Feng, Lixing, Zhu, Mengli, Shen, Qiang, Fang, Yanfen, Liu, Xuan, Zhang, Xiongwen
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895449/
https://ncbi.nlm.nih.gov/pubmed/31815040
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