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Targeting NEK2 as a promising therapeutic approach for cancer treatment

Never in Mitosis (NIMA) Related Kinase 2 (NEK2) plays a key role in regulating mitotic processes, including centrosome duplication and separation, microtubule stabilization, kinetochore attachment and spindle assembly checkpoint. NEK2 is aberrantly overexpressed in a wide variety of human cancers an...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Fang, Yanfen, Zhang, Xiongwen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889274/
https://ncbi.nlm.nih.gov/pubmed/27019372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1152430
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