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Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity
NEK2 is a conserved mitotic regulator critical for cell cycle progression. Aberrant expression of NEK2 has been found in a variety of human cancers, making it an attractive molecular target for the design of novel anticancer therapeutics. In the present study, we have identified a novel compound MBM...
Tallennettuna:
| Julkaisussa: | Oncotarget |
|---|---|
| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Impact Journals LLC
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5346717/ https://ncbi.nlm.nih.gov/pubmed/27764815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12687 |
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