Engineering DNA recognition and allosteric response properties of TetR family proteins by using a module-swapping strategy

The development of synthetic biological systems requires modular biomolecular components to flexibly alter response pathways. In previous studies, we have established a module-swapping design principle to engineer allosteric response and DNA recognition properties among regulators in the LacI family...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Dimas, Rey P, Jordan, Benjamin R, Jiang, Xian-Li, Martini, Catherine, Glavy, Joseph S, Patterson, Dustin P, Morcos, Faruck, Chan, Clement T Y
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Synthetic Biology and Bioengineering
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895282/
https://ncbi.nlm.nih.gov/pubmed/31392336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz666
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