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LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT)

Volume-regulated anion channels (VRAC) are chloride channels activated in response to osmotic stress to regulate cellular volume and also participate in other cellular processes, including cell division and cell death. Recently, members of the LRRC8 family have been identified as the main contributo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Friard, Jonas, Corinus, Alain, Cougnon, Marc, Tauc, Michel, Pisani, Didier F., Duranton, Christophe, Rubera, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895240/
https://ncbi.nlm.nih.gov/pubmed/31804464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2167-z
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