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LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT)

Volume-regulated anion channels (VRAC) are chloride channels activated in response to osmotic stress to regulate cellular volume and also participate in other cellular processes, including cell division and cell death. Recently, members of the LRRC8 family have been identified as the main contributo...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Friard, Jonas, Corinus, Alain, Cougnon, Marc, Tauc, Michel, Pisani, Didier F., Duranton, Christophe, Rubera, Isabelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895240/
https://ncbi.nlm.nih.gov/pubmed/31804464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2167-z
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