Direct nano-electrospray ionization tandem mass spectrometry for the quantification and identification of metronidazole in its dosage form and human urine

A rapid, sensitive and direct nano-electrospray ionization-tandem mass spectrometry (NS-ESI-MS/MS) method, using an offline nanospray (NS) capillary, has been developed and validated for the analysis of metronidazole (MTZ). A mixture of 2 µl MTZ sample solution prepared in an ionization solvent cons...

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Bibliographic Details
Published in:R Soc Open Sci
Main Authors: Amer, Sara, Zarad, Walaa, El-Gendy, Heba, Abdel-Salam, Randa, Hadad, Ghada, Masujima, Tsutomu, Emara, Samy
Format: Artigo
Language:Inglês
Published: The Royal Society 2019
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894584/
https://ncbi.nlm.nih.gov/pubmed/31827866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.191336
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