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Somatostatin Receptor Subtype-4 Regulates mRNA Expression of Amyloid-Beta Degrading Enzymes and Microglia Mediators of Phagocytosis in Brains of 3xTg-AD Mice

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in memory and cognitive impairment. The use of somatostatin receptor subtype-4 (SSTR(4)) agonists have been proposed for AD treatment. This study investigated the effects of selective SSTR(4) agonist NNC 26–9100 on mRNA e...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Sandoval, Karin, Umbaugh, David, House, Austin, Crider, Albert, Witt, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894394/
https://ncbi.nlm.nih.gov/pubmed/31630317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-019-02890-6
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