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In Vivo Synaptic Density Imaging with (11)C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease
(11)C-UCB-J is a new PET tracer for synaptic density imaging. Recently, we conducted (11)C-UCB-J PET on patients with mild cognitive impairment or early Alzheimer disease (AD) and found a 41% decrease in specific binding in the hippocampus compared with healthy subjects. We hypothesized that (11)C-U...
שמור ב:
| הוצא לאור ב: | J Nucl Med |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Society of Nuclear Medicine
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6894376/ https://ncbi.nlm.nih.gov/pubmed/31101744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.223867 |
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