In Vivo Synaptic Density Imaging with (11)C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease

(11)C-UCB-J is a new PET tracer for synaptic density imaging. Recently, we conducted (11)C-UCB-J PET on patients with mild cognitive impairment or early Alzheimer disease (AD) and found a 41% decrease in specific binding in the hippocampus compared with healthy subjects. We hypothesized that (11)C-U...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Nucl Med
Principais autores: Toyonaga, Takuya, Smith, Levi M., Finnema, Sjoerd J., Gallezot, Jean-Dominique, Naganawa, Mika, Bini, Jason, Mulnix, Tim, Cai, Zhengxin, Ropchan, Jim, Huang, Yiyun, Strittmatter, Stephen M., Carson, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Nuclear Medicine 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894376/
https://ncbi.nlm.nih.gov/pubmed/31101744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.223867
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados