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Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems
We report that placental growth factor (PlGF) negatively affects the endothelial cell (EC) barrier function through a novel regulatory mechanism. The PlGF mAb promotes (but recombinant protein disrupts) EC barrier function, thus affecting the barrier-forming protein levels, membrane distribution, an...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | FASEB J |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Federation of American Societies for Experimental Biology
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6894064/ https://ncbi.nlm.nih.gov/pubmed/31585507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901353R |
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