Inhibition of histone deacetylase 3 by MiR-494 alleviates neuronal loss and improves neurological recovery in experimental stroke

HDAC3 is an essential negative regulator of neuronal plasticity and memory formation. Although a chemical inhibitor has been invented, little is known about its endogenous modulators. We explored whether miR-494 affects HDAC3-mediated neuronal injury following acute ischemic stroke. A substantial in...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Zhao, Haiping, Li, Guangwen, Zhang, Sijia, Li, Fangfang, Wang, Rongliang, Tao, Zhen, Ma, Qingfeng, Han, Ziping, Yan, Feng, Fan, Junfen, Li, Lingzhi, Ji, Xunming, Luo, Yumin
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893973/
https://ncbi.nlm.nih.gov/pubmed/31510852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19875201
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