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Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

The Zika virus (ZIKV) is a member of the Flaviviridae family and an important human pathogen. Most pathogenic viruses encode proteins that interfere with the activation of host innate immune responses. Like other flaviviruses, ZIKV interferes with the expression of interferon (IFN) genes and inhibit...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Lundberg, Rickard, Melén, Krister, Westenius, Veera, Jiang, Miao, Österlund, Pamela, Khan, Hira, Vapalahti, Olli, Julkunen, Ilkka, Kakkola, Laura
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893776/
https://ncbi.nlm.nih.gov/pubmed/31690057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11111024
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