The Drosophila CPEB Protein Orb Specifies Oocyte Fate by a 3′UTR-Dependent Autoregulatory Loop

orb encodes one of the two fly CPEB proteins. These widely conserved proteins bind to the 3′UTRs of target messenger RNAs (mRNAs) and activate or repress their translation. We show here that a positive autoregulatory loop driven by the orb gene propels the specification of oocyte identity in Drosoph...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Barr, Justinn, Gilmutdinov, Rudolf, Wang, Linus, Shidlovskii, Yulii, Schedl, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2019
Pynciau:
Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893371/
https://ncbi.nlm.nih.gov/pubmed/31594794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302687
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