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The Drosophila CPEB Protein Orb Specifies Oocyte Fate by a 3′UTR-Dependent Autoregulatory Loop

orb encodes one of the two fly CPEB proteins. These widely conserved proteins bind to the 3′UTRs of target messenger RNAs (mRNAs) and activate or repress their translation. We show here that a positive autoregulatory loop driven by the orb gene propels the specification of oocyte identity in Drosoph...

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Bibliografski detalji
Izdano u:Genetics
Glavni autori: Barr, Justinn, Gilmutdinov, Rudolf, Wang, Linus, Shidlovskii, Yulii, Schedl, Paul
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2019
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893371/
https://ncbi.nlm.nih.gov/pubmed/31594794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302687
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