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Endoplasmic reticulum Ca(2+) release causes Rieske iron–sulfur protein-mediated mitochondrial ROS generation in pulmonary artery smooth muscle cells
Mitochondrial reactive oxygen species (ROS) cause Ca(2+) release from the endoplasmic reticulum (ER) via ryanodine receptors (RyRs) in pulmonary artery smooth muscle cells (PASMCs), playing an essential role in hypoxic pulmonary vasoconstriction (HPV). Here we tested a novel hypothesis that hypoxia-...
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| Опубликовано в: : | Biosci Rep |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893167/ https://ncbi.nlm.nih.gov/pubmed/31710081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20192414 |
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