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Moracin attenuates LPS-induced inflammation in nucleus pulposus cells via Nrf2/HO-1 and NF-κB/TGF-β pathway

The present study was designed to investigate the protective effect of moracin on primary culture of nucleus pulposus cells in intervertebral disc and explore the underlying mechanism. Moracin treatment significantly inhibited the LPS-induced inflammatory cytokine accumulation (IL-1β, IL-6 and TNF-α...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Gu, Ronghe, Huang, Zonggui, Liu, Huijiang, Qing, Qiwen, Zhuan, Zou, Yang, Lijing, Su, Zhongyi, Huang, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893166/
https://ncbi.nlm.nih.gov/pubmed/31729530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20191673
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