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Spatio-temporal modeling and live-cell imaging of proteolysis in the 4D microenvironment of breast cancer

Cells grown in three dimensions (3D) within natural extracellular matrices or synthetic scaffolds more closely recapitulate the phenotype of those cells within tissues in regard to normal developmental and pathobiological processes. This includes degradation of the surrounding stroma as the cells mi...

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Bibliographic Details
Published in:Cancer Metastasis Rev
Main Authors: Ji, Kyungmin, Sameni, Mansoureh, Osuala, Kingsley, Moin, Kamiar, Mattingly, Raymond R., Sloane, Bonnie F.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893099/
https://ncbi.nlm.nih.gov/pubmed/31605250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-019-09810-8
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