Stem Cell Modeling of Neuroferritinopathy Reveals Iron as a Determinant of Senescence and Ferroptosis during Neuronal Aging

Neuroferritinopathy (NF) is a movement disorder caused by alterations in the L-ferritin gene that generate cytosolic free iron. NF is a unique pathophysiological model for determining the direct consequences of cell iron dysregulation. We established lines of induced pluripotent stem cells from fibr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cell Reports
मुख्य लेखकों: Cozzi, Anna, Orellana, Daniel I., Santambrogio, Paolo, Rubio, Alicia, Cancellieri, Cinzia, Giannelli, Serena, Ripamonti, Maddalena, Taverna, Stefano, Di Lullo, Giulia, Rovida, Ermanna, Ferrari, Maurizio, Forni, Gian Luca, Fiorillo, Chiara, Broccoli, Vania, Levi, Sonia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6893074/
https://ncbi.nlm.nih.gov/pubmed/31587993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.09.002
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