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Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Bone morphogenetic proteins (BMPs) are secreted ligands of the transforming growth factor-β (TGF-β) family that control embryonic patterning, as well as tissue development and homeostasis. Loss of function mutations in the type II BMP receptor BMPR2 are the leading cause of pulmonary arterial hypert...
Gorde:
| Argitaratua izan da: | Sci Rep |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group UK
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892941/ https://ncbi.nlm.nih.gov/pubmed/31797984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54830-7 |
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