Renewed proliferation in adult mouse cochlea and regeneration of hair cells

The adult mammalian inner ear lacks the capacity to divide or regenerate. Damage to inner ear generally leads to permanent hearing loss in humans. Here, we present that reprogramming of the adult inner ear induces renewed proliferation and regeneration of inner ear cell types. Co-activation of cell...

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Udgivet i:Nat Commun
Main Authors: Shu, Yilai, Li, Wenyan, Huang, Mingqian, Quan, Yi-Zhou, Scheffer, Deborah, Tian, Chunjie, Tao, Yong, Liu, Xuezhong, Hochedlinger, Konrad, Indzhykulian, Artur A., Wang, Zhengmin, Li, Huawei, Chen, Zheng-Yi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892913/
https://ncbi.nlm.nih.gov/pubmed/31797926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13157-7
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