Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure

Anhedonia is a core symptom of several psychiatric disorders but its biological underpinnings are poorly understood. We performed a genome-wide association study of state anhedonia in 375,275 UK Biobank participants and assessed for genetic correlation between anhedonia and neuropsychiatric conditio...

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Pubblicato in:Transl Psychiatry
Autori principali: Ward, Joey, Lyall, Laura M., Bethlehem, Richard A. I., Ferguson, Amy, Strawbridge, Rona J., Lyall, Donald M., Cullen, Breda, Graham, Nicholas, Johnston, Keira J. A., Bailey, Mark E. S., Murray, Graham K., Smith, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892870/
https://ncbi.nlm.nih.gov/pubmed/31797917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0635-y
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