Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

BACKGROUND: Circadian rhythms are fundamental to health and are particularly important for mental wellbeing. Disrupted rhythms of rest and activity are recognised as risk factors for major depressive disorder and bipolar disorder. METHODS: We conducted a genome-wide association study (GWAS) of low r...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ferguson, Amy, Lyall, Laura M., Ward, Joey, Strawbridge, Rona J., Cullen, Breda, Graham, Nicholas, Niedzwiedz, Claire L., Johnston, Keira J.A., MacKay, Daniel, Biello, Stephany M., Pell, Jill P., Cavanagh, Jonathan, McIntosh, Andrew M., Doherty, Aiden, Bailey, Mark E.S., Lyall, Donald M., Wyse, Cathy A., Smith, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154782/
https://ncbi.nlm.nih.gov/pubmed/30120083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.004
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