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Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

BACKGROUND: Circadian rhythms are fundamental to health and are particularly important for mental wellbeing. Disrupted rhythms of rest and activity are recognised as risk factors for major depressive disorder and bipolar disorder. METHODS: We conducted a genome-wide association study (GWAS) of low r...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Ferguson, Amy, Lyall, Laura M., Ward, Joey, Strawbridge, Rona J., Cullen, Breda, Graham, Nicholas, Niedzwiedz, Claire L., Johnston, Keira J.A., MacKay, Daniel, Biello, Stephany M., Pell, Jill P., Cavanagh, Jonathan, McIntosh, Andrew M., Doherty, Aiden, Bailey, Mark E.S., Lyall, Donald M., Wyse, Cathy A., Smith, Daniel J.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154782/
https://ncbi.nlm.nih.gov/pubmed/30120083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.004
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