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Antisense Oligodeoxynucleotide Perfusion Blocks Gene Expression of Synaptic Plasticity-related Proteins without Inducing Compensation in Hippocampal Slices

The elucidation of the molecular mechanisms of long-term synaptic plasticity has been hindered by both the compensation that can occur after chronic loss of the core plasticity molecules and by ex vivo conditions that may not reproduce in vivo plasticity. Here we describe a novel method to rapidly s...

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Bibliografske podrobnosti
izdano v:Bio Protoc
Main Authors: Tsokas, Panayiotis, Rivard, Bruno, Hsieh, Changchi, Cottrell, James E., Fenton, André Antonio, Sacktor, Todd Charlton
Format: Artigo
Jezik:Inglês
Izdano: Bio-Protocol 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892586/
https://ncbi.nlm.nih.gov/pubmed/31803793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3387
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