Phenotypic proteomic profiling identifies a landscape of targets for circadian clock–modulating compounds

Determining the exact targets and mechanisms of action of drug molecules that modulate circadian rhythms is critical to develop novel compounds to treat clock-related disorders. Here, we have used phenotypic proteomic profiling (PPP) to systematically determine molecular targets of four circadian pe...

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Sparad:
Bibliografiska uppgifter
I publikationen:Life Sci Alliance
Huvudupphovsmän: Ray, Sandipan, Lach, Radoslaw, Heesom, Kate J, Valekunja, Utham K, Encheva, Vesela, Snijders, Ambrosius P, Reddy, Akhilesh B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Life Science Alliance LLC 2019
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892409/
https://ncbi.nlm.nih.gov/pubmed/31792063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900603
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