Phenotypic proteomic profiling identifies a landscape of targets for circadian clock–modulating compounds

Determining the exact targets and mechanisms of action of drug molecules that modulate circadian rhythms is critical to develop novel compounds to treat clock-related disorders. Here, we have used phenotypic proteomic profiling (PPP) to systematically determine molecular targets of four circadian pe...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Ray, Sandipan, Lach, Radoslaw, Heesom, Kate J, Valekunja, Utham K, Encheva, Vesela, Snijders, Ambrosius P, Reddy, Akhilesh B
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892409/
https://ncbi.nlm.nih.gov/pubmed/31792063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900603
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