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KCC2 expression levels are reduced in post mortem brain tissue of Rett syndrome patients
Rett Syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG binding protein 2 (MECP2) gene. Deficient K(+)-Cl(—)co-transporter 2 (KCC2) expression is suggested to play a key role in the neurodevelopmental delay in RTT patients’ neuronal networks. KCC2 is a major player...
Enregistré dans:
| Publié dans: | Acta Neuropathol Commun |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892240/ https://ncbi.nlm.nih.gov/pubmed/31796123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0852-x |
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