The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

An impairment of amyloid β-peptide (Aβ) clearance is suggested to play a key role in the pathogenesis of sporadic Alzheimer’s disease (AD). Amyloid degradation is mediated by various mechanisms including fragmentation by enzymes like neprilysin, matrix metalloproteinases (MMPs) and a recently identi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kirabali, Tunahan, Rigotti, Serena, Siccoli, Alessandro, Liebsch, Filip, Shobo, Adeola, Hock, Christoph, Nitsch, Roger M., Multhaup, Gerhard, Kulic, Luka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892233/
https://ncbi.nlm.nih.gov/pubmed/31796114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0846-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados