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Dichotomous Role of Plasmin in Regulation of Macrophage Function after Acetaminophen Overdose

Kupffer cells and monocyte-derived macrophages are critical for liver repair after acetaminophen (APAP) overdose. These cells produce promitogenic cytokines and growth factors, and they phagocytose dead cell debris, a process that is critical for resolution of inflammation. The factors that regulate...

詳細記述

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書誌詳細
出版年:Am J Pathol
主要な著者: Roth, Katherine, Strickland, Jenna, Joshi, Nikita, Deng, Meihong, Kennedy, Rebekah C., Rockwell, Cheryl E., Luyendyk, James P., Billiar, Timothy R., Copple, Bryan L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892227/
https://ncbi.nlm.nih.gov/pubmed/31381887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.07.003
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