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DNA‐Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On‐DNA Suzuki, Sonogashira, and Buchwald Reactions

Using (hetero)aryl fluorosulfonates as versatile electrophiles, facile on‐DNA cross‐coupling reactions of Suzuki, Sonogashira, and Buchwald are reported here. Notably, all of these reactions show excellent functional group tolerance, mild reaction conditions (relative low temperature and open to air...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Xu, Hongtao, Ma, Fei, Wang, Nan, Hou, Wei, Xiong, Huan, Lu, Fengping, Li, Jie, Wang, Shuyue, Ma, Peixiang, Yang, Guang, Lerner, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891896/
https://ncbi.nlm.nih.gov/pubmed/31832315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201901551
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