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CagA Effector Protein in Helicobacter pylori-Infected Human Gastric Epithelium in Vivo: From Bacterial Core and Adhesion/Injection Clusters to Host Cell Proteasome-Rich Cytosol

A key role in the carcinogenic action of Helicobacter pylori is played by the effector protein CagA, the first identified oncoprotein of the bacterial world. However, the present knowledge in regard to the bacterial injection of CagA into epithelial cells (through a type IV secretion system) and its...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Necchi, Vittorio, Ricci, Vittorio, Sommi, Patrizia, Solcia, Enrico
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891489/
https://ncbi.nlm.nih.gov/pubmed/31731531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11110618
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