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Multistep activation of the Helicobacter pylori effector CagA

Chronic infection with the Gram-negative bacterium Helicobacter pylori is a major risk factor for the development of gastric cancer. Accumulating evidence indicates that the H. pylori virulence determinant cytotoxin-associated gene A (CagA) has a key oncogenic role in the process. Certain biological...

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Autor principal: Müller, Anne
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314475/
https://ncbi.nlm.nih.gov/pubmed/22378039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61578
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