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Hydrogen peroxide depolarizes mitochondria and inhibits IP(3)-evoked Ca(2+) release in the endothelium of intact arteries

Hydrogen peroxide (H(2)O(2)) is a mitochondrial-derived reactive oxygen species (ROS) that regulates vascular signalling transduction, vasocontraction and vasodilation. Although the physiological role of ROS in endothelial cells is acknowledged, the mechanisms underlying H(2)O(2) regulation of signa...

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Detalhes bibliográficos
Publicado no:Cell Calcium
Main Authors: Zhang, Xun, Lee, Matthew D., Wilson, Calum, McCarron, John G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891240/
https://ncbi.nlm.nih.gov/pubmed/31715384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2019.102108
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