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Regulation of MT dynamics via direct binding of an Abl family kinase

Abl family kinases are essential regulators of cell shape and movement. Genetic studies revealed functional interactions between Abl kinases and microtubules (MTs), but the mechanism by which Abl family kinases regulate MTs remains unclear. Here, we report that Abl2 directly binds to MTs and regulat...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Hu, Yuhan, Lyu, Wanqing, Lowery, Laura Anne, Koleske, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891085/
https://ncbi.nlm.nih.gov/pubmed/31699690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812144
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