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Regulation of MT dynamics via direct binding of an Abl family kinase

Abl family kinases are essential regulators of cell shape and movement. Genetic studies revealed functional interactions between Abl kinases and microtubules (MTs), but the mechanism by which Abl family kinases regulate MTs remains unclear. Here, we report that Abl2 directly binds to MTs and regulat...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Hu, Yuhan, Lyu, Wanqing, Lowery, Laura Anne, Koleske, Anthony J.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891085/
https://ncbi.nlm.nih.gov/pubmed/31699690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201812144
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