Marked TGF-β-regulated miRNA expression changes in both COPD and control lung fibroblasts

COPD is associated with disturbed tissue repair, possibly due to TGF-β-regulated miRNA changes in fibroblasts. Our aim was to identify TGF-β-regulated miRNAs and their differential regulation and expression in COPD compared to control fibroblasts. Small RNA sequencing was performed on TGF-β-stimulat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ong, J., Faiz, A., Timens, W., van den Berge, M., Terpstra, M. M., Kok, K., van den Berg, A., Kluiver, J., Brandsma, C. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890791/
https://ncbi.nlm.nih.gov/pubmed/31796837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54728-4
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