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Conversion of Cytochrome P450 2D6 of Human Into a FRET-Based Tool for Real-Time Monitoring of Ajmalicine in Living Cells

Ajmalicine is naturally present in the root bark of Catharanthus roseus L. and Rauvolfia serpentina (L.) Benth ex.Kurz. It has been extensively utilized in the treatment of hypertension across the world. The increased demand, overconsumption, and low content of the alkaloid in the plants have raised...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Ambrin, Ghazala, Ahmad, Mohammad, Alqarawi, Abdulaziz A., Hashem, Abeer, Abd_Allah, Elsayed Fathi, Ahmad, Altaf
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890717/
https://ncbi.nlm.nih.gov/pubmed/31828069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00375
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