Conversion of Cytochrome P450 2D6 of Human Into a FRET-Based Tool for Real-Time Monitoring of Ajmalicine in Living Cells

Ajmalicine is naturally present in the root bark of Catharanthus roseus L. and Rauvolfia serpentina (L.) Benth ex.Kurz. It has been extensively utilized in the treatment of hypertension across the world. The increased demand, overconsumption, and low content of the alkaloid in the plants have raised...

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Bibliografiska uppgifter
I publikationen:Front Bioeng Biotechnol
Huvudupphovsmän: Ambrin, Ghazala, Ahmad, Mohammad, Alqarawi, Abdulaziz A., Hashem, Abeer, Abd_Allah, Elsayed Fathi, Ahmad, Altaf
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Bioengineering and Biotechnology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890717/
https://ncbi.nlm.nih.gov/pubmed/31828069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00375
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