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Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex

Occludin (OCLN) mutations cause human microcephaly and cortical malformation. A tight junction component thought absent in neuroepithelium after neural tube closure, OCLN isoform-specific expression extends into corticogenesis. Full-length and truncated isoforms localize to neuroprogenitor centrosom...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bendriem, Raphael M, Singh, Shawn, Aleem, Alice Abdel, Antonetti, David A, Ross, M Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890460/
https://ncbi.nlm.nih.gov/pubmed/31794381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49376
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