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Neuroprotective Effect of S-trans, Trans-farnesylthiosalicylic Acid via Inhibition of RAS/ERK Pathway for the Treatment of Alzheimer’s Disease

BACKGROUND: Alzheimer’s disease (AD), a leading cause of dementia, becomes a serious health issue for individuals and society around the world. AD is a neurodegenerative disease characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFT) and the loss of large numbers...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Xiang, Wang, Yu, Zhu, Yiyi, Yan, Luxia, Zhao, Liandong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6890185/
https://ncbi.nlm.nih.gov/pubmed/31819374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S233283
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