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Molecular Dynamics Study of the Hybridization between RNA and Modified Oligonucleotides

MicroRNAs (miRNAs) are attractive drug candidates for many diseases as they can modulate the expression of gene networks. Recently, we discovered that DNAs targeting microRNA-22–3p (miR-22–3p) hold the potential for treating obesity and related metabolic disorders (type 2 diabetes mellitus, hyperlip...

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Bibliografiske detaljer
Udgivet i:J Chem Theory Comput
Main Authors: Jing, Zhifeng, Qi, Rui, Thibonnier, Marc, Ren, Pengyu
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889957/
https://ncbi.nlm.nih.gov/pubmed/31553600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b00519
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