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Molecular Dynamics Study of the Hybridization between RNA and Modified Oligonucleotides
MicroRNAs (miRNAs) are attractive drug candidates for many diseases as they can modulate the expression of gene networks. Recently, we discovered that DNAs targeting microRNA-22–3p (miR-22–3p) hold the potential for treating obesity and related metabolic disorders (type 2 diabetes mellitus, hyperlip...
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| Publicado no: | J Chem Theory Comput |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6889957/ https://ncbi.nlm.nih.gov/pubmed/31553600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b00519 |
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