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Sample size re-estimation in crossover trials: application to the AIM HY-INFORM study

BACKGROUND: Crossover designs are commonly utilised in randomised controlled trials investigating treatments for long-term chronic illnesses. One problem with this design is its inherent repeated measures necessitate the availability of an estimate of the within-person standard deviation (SD) to per...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Wych, Julie, Grayling, Michael J., Mander, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889633/
https://ncbi.nlm.nih.gov/pubmed/31791376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3724-6
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