IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment

BACKGROUND: Interleukin-33 (IL-33) belongs to the IL-1 cytokine family and resides in the nuclei of various cell types. In the neural retina, IL-33 is predominately expressed in Müller cells although its role in health and disease is ill-defined. Müller cell gliosis is a critical response during the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroinflammation
Prif Awduron: Augustine, Josy, Pavlou, Sofia, Ali, Imran, Harkin, Kevin, Ozaki, Ema, Campbell, Matthew, Stitt, Alan W., Xu, Heping, Chen, Mei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889479/
https://ncbi.nlm.nih.gov/pubmed/31796062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1625-y
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