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Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2(Akita) diabetic mouse

Current therapies that target vascular endothelial growth factor (VEGF) have become a mainstream therapy for the management of diabetic macular oedema. The treatment involves monthly repeated intravitreal injections of VEGF inhibitors. VEGF is an important growth factor for many retinal cells, inclu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hombrebueno, Jose R., Ali, Imran HA., Xu, Heping, Chen, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680939/
https://ncbi.nlm.nih.gov/pubmed/26671074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18316
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