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Prediction of leukocyte counts during paediatric acute lymphoblastic leukaemia maintenance therapy

Maintenance chemotherapy with oral 6-mercaptopurine and methotrexate remains a cornerstone of modern therapy for acute lymphoblastic leukaemia. The dosage and intensity of therapy are based on surrogate markers such as peripheral blood leukocyte and neutrophil counts. Dosage based leukocyte count pr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Karppinen, Santeri, Lohi, Olli, Vihola, Matti
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889389/
https://ncbi.nlm.nih.gov/pubmed/31792398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54492-5
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