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Monocarbonyl curcumin analog A2 potently inhibits angiogenesis by inducing ROS-dependent endothelial cell death

Excessive and abnormal vessel growth plays a critical role in the pathogenesis of many diseases, such as cancer. Angiogenesis is one of the hallmarks of cancer growth, invasion, and metastasis. Discovery of novel antiangiogenic agents would provide new insights into the mechanisms of angiogenesis, a...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Liu, Bin, Cui, Liu-su, Zhou, Bo, Zhang, Ling-ling, Liu, Zhi-hui, Zhang, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889379/
https://ncbi.nlm.nih.gov/pubmed/31000770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0224-x
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