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Monocarbonyl Curcumin Analogs: Heterocyclic Pleiotropic Kinase Inhibitors that Mediate Anti-Cancer Properties

Curcumin is a biologically active component of curry powder. A structurally-related class of mimetics possesses similar anti-inflammatory and anticancer properties. Mechanism has been examined by exploring kinase inhibition trends. In a screen of 50 kinases relevant to many forms of cancer, one memb...

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Detalhes bibliográficos
Main Authors: Brown, Andrew, Shi, Qi, Moore, Terry W., Yoon, Younghyoun, Prussia, Andrew, Maddox, Clinton, Liotta, Dennis C., Shim*, Hyunsuk, Snyder*, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927397/
https://ncbi.nlm.nih.gov/pubmed/23550937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4002692
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